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KMID : 0828520130170040223
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Journal of the Korean Geriatrics Society
2013 Volume.17 No. 4 p.223 ~ p.227
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Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation
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Kim Dae-Jung
Lee Sang-Chil
Park Gi-Soo
Kim Gyung-Jung
Hwang Won-Tae
Lee Chang-Soo
Lee Moo-Hyun
Hahn Dae-Hee
Koh Hyeon-Cheol
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Abstract
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Amiodarone is an antiarrhythmic drug known to have adverse effects on multiple organs. Most studies have reported the side effects of the drug, which may result from rapid administrations or from long-term, high dosage administrations. However, toxicity issues have also been reported from patients administered with low doses of the drug for a long period of time. Here we report a case of an 82-year-old female who had shown symptoms and signs of pulmonary, hepatic, and neurotoxicity after taking amiodarone for 14 months in order to treat her atrial fibrillation without regular outpatient follow-up. We highlight the importance of the recommended evaluations, including lung, liver, and thyroid functions, as well as the neurological examinations in patients treated with amiodarone for a long period of time during regular follow-up.
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KEYWORD
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Amiodarone, Pulmonary toxicity, Hepatic toxicity, Neurotoxicity
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